CancerCare Manitoba		  
 
 
Relevent Publications

 

Dr. Jim R. Davie: Introduction & Research Interest References

1. Reviews on chromatin structure and function

  1. Davie, J.R. & Hendzel, M.J. (1994) Multiple functions of dynamic histone acetylation. J. Cell. Biochem. 55, 98-105. Abstract
  2. Davie, J.R. (1995) The nuclear matrix and the regulation of chromatin organization & function. In: Structural and functional organization of the nuclear matrix; edited by Ronald Berezney & Kwang W. Jeon, Int. Rev. Cytol. 162A, 191-250. Abstract
  3. Davie, J.R. (1996) Histone modifications, chromatin structure, and the nuclear matrix. J.Cell.Biochem. 62, 149-157. Abstract
  4. Davie, J.R. (1997) Nuclear matrix, dynamic histone acetylation and transcriptionally active chromatin. Mol.Biol.Rep., 24, 197-209.  Abstract
  5. Davie, J.R. (1998) Covalent modifications of histones: expression from chromatin templates. Curr.Opin.Genet.Dev. 8:173-178. Abstract
  6. Davie, J.R., Samuel, S., Spencer, V., Bajno, L., Sun, J.-M., Chen, H.Y. & Holth, L.T. (1998) Nuclear matrix: application to diagnosis of cancer and role in transcription and modulation of chromatin structure. GeneTher.Mol.Biol. 1:509-528. Abstract
  7. Holth, L.T., Chadee, D.N., Spencer, V.A., Samuel, S.K., Safneck, J.R. & Davie, J.R. (1998) Chromatin, nuclear matrix and the cytoskeleton: role of cell structure in neoplastic transformation. Int.J.Oncol. 13:827-37. Abstract
  8. Davie, J.R. & Chadee, D.N. (1998) Regulation and regulatory parameters of histone modifications. J.Cell.Biochem. 30131:203-213. Abstract
2. Reviews on nuclear matrix proteins and cancer

  1. Chen, H.Y., Sun, J.-M., Hendzel, M.J., Rattner, J.B. & Davie, J.R. (1996) Changes in the nuclear matrix of chicken erythrocytes that accompany maturation. Biochem. J., 320, 257-265.  Abstract
  2. Coutts, A.S., Davie, J.R., Dotzlaw, H. & Murphy, L.C. (1996) Estrogen regulation of nuclear matrix-intermediate filament proteins in human breast cancer cells. J.Cell.Biochem. 63, 174-184. Abstract 
  3. Samuel, S.K., Minish,T.M. & Davie, J.R. (1997) Altered nuclear matrix proteins in oncogene transformed mouse fibroblasts exhibiting high metastatic potential. Cancer Res. 57, 147-151. Abstract
  4. Samuel, S.K., Minish, T.M. & Davie, J.R. (1997) Nuclear matrix proteins in well and poorly differentiated human breast cancer cells. J. Cell. Biochem. 66, 9-15. Abstract
  5. Spencer, V.A., Coutts, A.S., Samuel, S.K., Murphy, L.C. & Davie, J.R. (1998) Estrogen regulates the association of intermediate filament proteins with nuclear DNA in human breast cancer cells. J.Biol.Chem 273:29093-29097.  Abstract
  6. Fischer, A.H., Chadee, D.N., Wright, J.A., Gansler, T.S. & Davie, J.R. (1998) Ras-associated nuclear structural change appears functionally significant and independent of the mitotic signaling pathway. J.Cell.Biochem. 70:130-140. Abstract

3. Reviews on nuclear matrix and transcription factors

  1. Sun, J.-M., Chen, H.Y. & Davie, J.R. (1994) Nuclear factor 1 is a component of the nuclear matrix. J. Cell. Biochem. 55, 252-263. Abstract
  2. Sun, J.-M., Chen, H.Y., Litchfield, D.W. & Davie, J.R. (1996) Developmental changes in transcription factors associated ith the nuclear matrix of chicken erythrocytes. J.Cell.Biochem. 62, 454-466.  Abstract
  3. Oesterreich, S., Lee, A.V., Sullivan, T.M., Samuel, S.K., Davie, J.R. & Fuqua, S.A.W. (1997) A novel nuclear matrix protein HET binds to and influences activity of the HSP27 promoter. J.Cell.Biochem. 67: 275-286. Abstract
  4. Samuel, S.K., Spencer, V.A., Bajno, L., Sun, J.-M., Holth, L.T., Oesterreich, S. & Davie, J.R. (1998) In situ cross-linking by cisplatin of nuclear matrix-bound transcription factors to nuclear DNA of human breast cancer cells. Cancer Res. 58:3004-3008. Abstract
  5. Htun,H., Holth,L.T., Walker,D., Davie,J.R. & Hager,G.L. (1999) Localization of a human estrogen receptor ( tagged with a green fluorescent protein in human cells. Mol Biol Cell. 1999 Feb;10(2):471-86. Abstract

4. Reviews on histone acetylation, methylation and ubiquitination

             Histone Acetylation
  1. Hendzel, M.J., Delcuve, G.P. and Davie, J.R. (1991) Histone deacetylase is a component of the internal nuclear matrix. J. Biol. Chem. 266, 21936-21942. Abstract
  2. Hendzel, M.J., Sun, J.-M., Chen, H.Y., Rattner, J.B. & Davie, J.R. (1994) Histone acetyltransferase is associated with the nuclear matrix. J. Biol. Chem. 269, 22894-22901. Abstract
  3. Waterborg, J.H., Robertson, A.J.M., Tatar, D.L., Borza, C.M. & Davie, J.R. (1995) Histone of Chlamydomonas reinhardtii: Synthesis, acetylation and methylation. Plant Physiol. 109, 393-407. Abstract
  4. Li, W., Chen, H.T. & Davie, J.R. (1996) Properties of chicken histone deacetylase associated with the nuclear matrix. Biochem. J. 314, 631-637. Abstract
  5. Yang, W.-M., Yao, Y.-L., Sun, J.-M., Davie, J.R. & Seto, E. (1997) Isolation and characterization of cDNAs corresponding to an additional member of the human histone deacetylase gene family. J.Biol.Chem. 272: 28001-28007. Abstract
  6. Heinzel, T., Lavinsky, R.M., Mullen, T.-M., Soderstrom, M., Laherty, C.D., Torchia, J.T., Yang, W.- M., Brard, G., Ngo,S.D., Davie, J.R., Seto, E., Eisenman, R.N., Rose, D.W., Glass, C.K. & Rosenfeld, M.G. (1997) A complex containing N-CoR, mSin3, and histone deacetylase mediates transcriptional repression. Nature 387, 43-48. Abstract
  7. Laherty, C.D., Yang, W.M., Sun, J.M., Davie, J.R., Seto, E. & Eisenman, R.N. (1997) Histone deacetylases associated with the mSin3 corepressor mediate Mad:Max transcriptional repression. Cell 89, 349-356. Abstract
  8. Lutterbach, B., Westendorf, J.J., Linggi, B., Patten, A., Moniwa, M., Davie, J.R., Huynh, K., Bardwell, V.J., Lavinsky, R.M., Rosenfeld, M.G., Seto, E. & Hiebert, S.W. (1998) ETO, a target of the t(8;21) in acute leukemia, interacts with the N-CoR and mSin3 corepressors. Mol.Cell.Biol. 18:7176-7184. Abstract
  9. Laherty, C.D., Billin, A.N., Lavinsky, R.M., Yochum, G.S., Bush, A.C., Sun, J.-M., Mullen, T.-M., Davie, J.R., Rose, D.W., Glass, C.K., Rosenfeld, M.G., Ayer, D.E. & Eisenman, R.N. (1998) SinAP30,a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors. Mol.Cell 2:33-42. Abstract
  10. Walia, H., Chen, H.Y., Sun, J.-M., Holth, L.T. & Davie, J.R. (1998) Histone acetylation is required to maintain the unfolded nucleosome structure associated with transcribing DNA. J.Biol.Chem. 273:14516-24522.  Abstract

    Histone acetylation and methylation
  11. Hendzel, M.J. and Davie, J.R. (1989) Distribution of methylated histones and histone methyltransferases in chicken erythrocyte chromatin. J. Biol. Chem. 264, 19208-19214. Abstract
  12. Hendzel, M.J. and Davie, J.R. (1991) Dynamically acetylated histones of chicken erythrocytes are selectively methylated.Biochem. J. 273, 753-758.Abstract
  13. Hendzel, M.J. and Davie, J.R. (1992) Acetylation and methylation of histones H3 and H4 in chicken immature erythrocytes are not directly coupled. Biochem. Biophys. Res. Commun. 185, 414-419. Abstract

    Histone ubiquitination
  14. Hendzel, M.J. and Davie, J.R. (1990) Nucleosomal histones of transcriptionally active/competent chromatin preferentially exchange with newly synthesized histones in quiescent chicken erythrocytes. Biochem. J. 271, 67-73. Abstract
  15. Davie, J.R. and Murphy, L.C. (1990) The level of ubiquitinated histone H2B in chromatin is coupled to on-goingtranscription. Biochemistry 29, 4752-4757.  Abstract
  16. Davie, J.R. & Murphy, L.C. (1994) Inhibition of transcription selectively reduces the level of ubiquitinated histone H2B in chromatin. Biochem. Biophys. Res. Commun. 203, 344-350. Abstract
  17. Mimnaugh, E.G., Chen, H.Y., Davie, J.R., Celis, J.E. & Neckers, L. (1997) Rapid deubiquitination of nucleosomal histones in human tumor cells caused by proteasome inhibitors and stress response inducers: effects on replication, transcription, translation, and the cellular stress response. Biochemistry 36:14418-14429. Abstract
  18. Chen, H.Y., Sun, J.-M., Zhang, Y., Davie, J.R. & Meistrich, M.L. (1998) Ubiquitination of histone H3 in elongating spermatids of rat testes. J.Biol.Chem. 273:13165-13169. Abstract

5. Reviews on histone phosphorylation

  1. Taylor, W.R., Chadee, D.N., Allis, C.D., Wright, J.A. & Davie, J.R. (1995) Fibroblasts transformed by combinations of ras, myc and mutant p53 exhibit increased phosphorylation of histone H1 that is independent of metastatic potential. FEBS Lett. 377, 51-53. Abstract
  2. Chadee, D.N., Taylor, W.R., Hurta, R.A.R., Allis, C.D., Wright, J.A. & Davie, J.R. (1995) Increased phosphorylation of histone H1 in mouse fibroblasts transformed with oncogenes or constitutively active mitogen-actviated protein kinase kinase. J.Biol.Chem. 270, 20098-20105. Abstract
  3. Nagaraja, S., Delcuve, G.P. & Davie, J.R. (1995) Differential compaction of transcriptionally competent and repressed chromatin reconstituted with histone H1 subtypes. Biochim. Biophys. Acta 1260, 207-214.  Abstract
  4. Chadee, D.N., Allis, C.D., Wright, J.A. & Davie, J.R. (1997) Histone H1b phosphorylation is dependent upon ongoing transcription and replication in normal and ras-transformed mouse fibroblasts. J. Biol. Chem. 272, 8113-8116. Abstract